Careers

Exosome Diagnostics, Inc. is commercializing minimally invasive molecular diagnostics in blood and urine to enable doctors to select optimal therapies for cancer and other diseases. The company's core technology is a proprietary diagnostic platform based on the discovery that circulating nanovesicles called exosomes contain unique genetic markers.

Exosome Diagnostics enjoys a culture that embraces innovation, critical thinking and a passion to succeed. If you are seeking an environment that is action oriented, provides a high level of accountability, encourages decision making and pursues simple, transparent and yet highly effective ways of working, please submit your resume.

Positions

Scientist – Bioinformatics (Munich)

We are currently seeking an experienced Bioinformatics Scientist for our Munich site. This position will be responsible for providing key technical, statistical and intellectual input into the analysis of sequencing and array data of urine- and blood-based exosome RNA from patients with cancer, metabolic and other diseases.

Candidates must be experienced in the field of next-generation sequencing data analysis and preferably also microarray data analysis. We expect that you will have a background in molecular biology or similar, as well as bioinformatics or statistics.

Key responsibilities include:

  • Analyze Next Gen Sequence data from exosome RNA derived from clinical samples.
  • Analyze microarray data from exosome RNA derived from clinical samples.
  • Derive genetic signatures and biomarkers, and evaluate their statistical validity.
  • Develop new algorithms and tools or modify existing ones to fit the needs for exosome RNA analysis.
  • Assist in the design of key experiments and company-wide project plans to advance the development and understanding of the molecular biology of exosomes.
  • Provide assistance and training when required to aid the development of other team members.
  • Contribute data and analysis to intellectual property filings and peer-reviewed publications.
  • Present thoughtful analysis and interact with the rest of the company's scientific staff and key stake holders, including our collaborator network of world-class hospitals and universities.

We expect that you:

  • Have a couple of years post-doc experience from academia or similar experience from a position in industry.
  • Are proficient in the use of bioinformatics tools and are experienced in the programming skills needed for the job.
  • Have a scientific publication record in leading journals and are up to date on current scientific literature in the field.
  • Can work independently and are deadline focused.
  • Are disciplined and organized and understand the importance of documenting your work.
  • Have a strong sense of integrity.
  • Enjoy a culture where strong work ethics are combined with good humor.
  • Are looking for an opportunity to contribute to significant research outside of large corporate structures.

A minimum of a PhD in molecular biology, computer science or other relevant field of study is required for this position. Exosome Diagnostics is an early-stage company with an entrepreneurial culture that encourages constructive input from its employees.

Interested candidates should submit a resume (Word or PDF format).

Research or Clinical Laboratory Manager

We are currently seeking an experienced research or clinical laboratory manager for our New York City laboratory. The ideal candidate will be comfortable working in a fast-paced environment, able to work independently, capable of problem solving and detail oriented. This position is responsible for managing the operational aspects of the laboratory, ensuring that the facilities, IT systems, instrumentation and laboratory supplies are in place and functioning properly to support company research efforts.

  • Problem solving — the individual identifies and resolves problems in a timely manner and gathers and analyzes information skillfully.
  • Oral communication — the individual speaks clearly and persuasively in positive or negative situations and conducts productive meetings.
  • Willingness to serve — the individual works to complete assignments on time to ensure successful research efforts, is able to work independently, sets expectations and works to build relationship with research staff.
  • Leadership — the individual inspires and motivates others to perform well, accepts feedback from others.
  • Management skills — the individual includes staff in planning, decision-making, facilitating and process improvement; makes self available to staff; provides regular performance feedback and is continously seeking to improvement operational processes.
  • Quality management — the individual looks for ways to improve and promote quality, and demonstrates accuracy and thoroughness.
  • Judgment — the individual displays willingness to make decisions, exhibits sound and accurate judgment and makes timely decisions.
  • Planning/organizing — the individual prioritizes and plans work activities, uses time efficiently and develops realistic action plans.

Interested candidates should submit a resume (Word or PDF format).

Research Scientist

We are currently seeking an experienced Research Scientist for our New York City laboratory. This position will be responsible for providing key technical and intellectual input into the development of urine- or blood-based exosome assays for cancer, metabolic and other diseases. Candidate must have strong technical aptitude and a creative drive to solve challenging technical issues. Must be skilled in the art of molecular biology, carefully document every aspect of the work, have a strong sense for details, and work in a organized and methodical manner. Key responsibilities include:

  • Assist in the design and execution of key experiments to advance the development and troubleshooting of the molecular-biology-based assays being designed.
  • Provide assistance and training when required to aid the development of other team members, including junior technicians.
  • Assist in the development of innovative solutions to achieve technology milestones.
  • Support constructive and positive internal communications processes.
  • Assist in defining and in developing innovative solutions to achieve technology milestones and to impact product improvements.
  • Work cross-functionally with counterparts to develop overall product development, research and technology strategy.
  • Maintain consistency, quality, standardization and discipline across product-development experiments.
  • Maintain customer focus and understand the needs of laboratorians, patients, physicians, regulators and third-party payors.
  • Must be able to work with human clinical samples (urine, blood and tissue).
  • Be updated on current scientific literature in the field.
  • Preference given to those applicants with expertise in qPCR, SNIP analysis, rare allele mutation analysis, molecular beacon, scorpion or taqman chemistries.

A minimum of a PhD in molecular biology, biochemistry or relevent field of study is required for this position. The ideal candidate will have in-depth scientific as well as technical knowledge of gene mutations and gene expression-profiling and experience handling small quantities of RNA. Some background in bioinformatics is highly desirable. Three referees will be required, preferably with one being the primary PhD mentor.

Interested candidates should submit a resume (Word or PDF format).

Laboratory Technician (NYC)

We are currently seeking an experienced lab technician for our New York City facility. The laboratory technologist will perform complex experiments to generate the data required to support the commercialization of exosome technology for diagnostic applicatons. The ideal candidate is capable of problem solving and of being detail oriented, and thrives on working in a focused environment. Relevant experience includes:

  • Familiarity with a variety of molecular biology techniques including nucleic acid extraction, amplification and detection.
  • Experience in virology, cancer biology, biochemistry or cell biology.
  • Previous work experience in a regulated laboratory (such as CLIA or GLP).
  • Strong analytical and problem-solving skills with experience with statistics, data analysis and data review.
  • The ability to teach basic technical procedures and the proper use and maintaintenance of equipment.
  • Excellent organizational skills, record-keeping skills and computer proficiency.
  • Ability to work and communicate well with multiple investigators and to manage multiple projects.
  • The individual should be able to work relatively independently and to help design protocols with appropriate controls.

A minimum of a Bachelors of Science degree in biological science, health science or clinical laboratory science and 1–3 years of experience performing molecular diagnostic testing in either the research or clinal laboratory settings.

Interested candidates should submit a resume (Word or PDF format).

Clinical Research Associate or Clinical Research Coordinator (NYC)

We are currently seeking an experienced clinical research associate (CCRA) or clinical resource coordinator (CCRC) based out of our New York City office to oversee and coordinate the implementation and management of research trials sample collection for company sponsored projects. The ideal candidate will be comfortable working in a fast paced environment, able to work independently, capable of problem solving and detail oriented. Primary responsibilities include:

  • Build and maintain excellent working relationships with primary clinical trial sites (e.g., research and technical staff, Clinical Trial Research Coordinators, Physician Investigators, hospital/office personnel) and ensure that the requirements of the company are met and maintained.
  • Catalog and store serum and urine from multiple sites.
  • Facilitate communication with physician investigators and others needed to conduct quality research.
  • Work positively in person, by phone and via written documentation with physicians, nursing staff, research and technical staff, co-workers and study representatives.
  • Communicate needs and requirements effectively, and convince others to follow a course of action.
  • Maintain detailed records and execute study logistics and feasibility plans for clinical trials as assigned. Provide accurate progress reports on clinical projects by writing assigned clinical portions of reports for submission to regulatory agencies, Institutional Review Boards, etc.
  • Remain current on regulatory/compliance standards and complete all study-related documentation and company clinical trials data according to IRB approved protocol, Standard Operating Procedures, study specifications and Good Clinical Practice.
  • Demonstrate general computer skills to include database use, data entry, report retrieval, forms design, and document editing abilities such as Microsoft Word, Excel project or PowerPoint.
  • Willing to travel on a limited basis.

A minimum of a B.S. in a science-related field or equivalent (four years) relevant experience in lieu of degree required. One year clinical experience in a health-care setting and/or clinical research required. Experience with cataloguing and storage of clinical serum and urine samples from multiple sites would be an advantage. Preferred qualification include Certification as a Clinical Research Coordinator (CCRC) or Associate (CCRA).

Interested candidates should submit a resume (Word or PDF format).