Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences

Nature Communications 2:180 (2011); Published online: 1 February 2011
DOI: 10.1038/ncomms1180 http://www.nature.com/ncomms/journal/v2/n2/full/ncomms1180.html
Authors: Leonora Balaj, Ryan Lessard, Lixin Dai, Yoon-Jae Cho, Scott L. Pomeroy, Xandra O. Breakefield and Johan Skog

Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease

Kidney International 78, 191–199 (July (2) 2010)
doi: 10.1038/ki.2010.106 http://www.nature.com/ki/journal/v78/n2/full/ki2010106a.html
Authors: Kevin C Miranda, Daniel T Bond, Mary McKee, Johan Skog, Teodor G Păunescu, Nicolas Da Silva, Dennis Brown and Leileata M Russo

Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer

British Journal of Cancer (2009) 100, 1603–1607.
doi: 10.1038/sj.bjc.6605058 http://www.nature.com/bjc/journal/v100/n10/full/6605058a.html
Authors: J Nilsson, J Skog, A Nordstrand, V Baranov, L Mincheva-Nilsson, X O Breakefield and A Widmark

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

Nature Cell Biology 10, 1470–1476 (2008); Published online: 16 November 2008
doi: 10.1038/ncb1800 http://www.nature.com/ncb/journal/v10/n12/abs/ncb1800.html
Authors: Johan Skog, Tom Würdinger, Sjoerd van Rijn, Dimphna H. Meijer, Laura Gainche, William T. Curry, Jr., Bob S. Carter, Anna M. Krichevsky and Xandra O. Breakefield

Use of exosome analysis to reveal glioma-specific genetic changes in patient serum

ASCO Annual Meeting — Chicago, IL (June 2011)
Authors: B. Carter¹, F. Hochberg², X. Breakefield², L. Balaj², S. Sivaraman², W. Curry², S.N. Kalkanis³, L. Loguidice³, L.M. Russo⁴, M. Noerhelm⁴, J. Skog^2,4
Affiliations: ¹University of California, San Diego, La Jolla, CA; ²Massachusetts General Hospital, Boston, MA, USA; ³Henry Ford Health System, Detroit, MI, USA; ⁴Exosome Diagnostics, New York, NY, USA

Genetic elements in tumor microvesicles

AACR 102nd Annual Meeting — Orlando, FL (April 2011)
Authors: Leonora Balaj¹, Ryan Lessard¹, Lixin Dai², Yoon-Jae Cho¹, Scott L. Pomeroy¹, Xandra O. Breakefield¹, Johan Skog^1,3
Affiliations: ¹Department of Neurology, Neurogenetics Unit, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA 02129; ²Department of Molecular Biology and Genetics and High Throughput Biology Center, The Johns Hopkins University School of Medicine, Baltimore, MD, USA 21205; ³Exosome Diagnostics, Inc. 3960 Broadway, New York, NY, USA 10032

Rapid isolation and analysis of urinary exosomes/microvesicles for nucleic acid based biomarker analysis

IWE – International Workshop on Exosomes — Paris (January 2011)
Authors: Daniel T. Bond¹, Leileata M. Russo^1,2
Affiliations: ¹Center for Systems Biology, Program in Membrane Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA 02124; ²Exosome Diagnostics, New York, NY, USA 10032

Tumor exosomes contain retrotransposon elements and amplified oncogene sequences

IWE – International Workshop on Exosomes — Paris (January 2011)
Authors: Leonora Balaj¹, Ryan Lessard¹, Lixin Dai², Yoon-Jae Cho¹, Scott L. Pomeroy¹, Xandra O. Breakefield¹, Johan Skog^1,3
Affiliations: ¹Department of Neurology, Neurogenetics Unit, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA 02129; ²Department of Molecular Biology and Genetics and High Throughput Biology Center, The Johns Hopkins University School of Medicine, Baltimore, MD, USA 21205; ³Exosome Diagnostics, Inc. 3960 Broadway, New York, NY, USA 10032

BEAMing PCR Analysis of Tumor Microvesicle RNA

IWE – International Workshop on Exosomes — Paris (January 2011)
Authors: Walter W. Chen, Leonora Balaj, Bob Carter, Fred Hochberg, Lin Dan Zhu, Sara Silverman, Linda M. Liau^*, Xandra O. Breakefield, Johan Skog
Affiliations: Neurology, Radiology and Neurosurgery Departments, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA 02115; ^*Neurosurgery Department, UCLA Medical Center, Santa Monica, CA, USA 90404

RNA expression patterns in serum exosomes from patients with glioblastoma multiforme

IWE – International Workshop on Exosomes — Paris (January 2011)
Authors: Mikkel Noerholm^1,2, Tobias B. Limperg^1,3, Leonora Balaj¹, Afshin Salehi⁴, Fred H. Hochberg¹, Bob Carter^1,4, Lin Dan Zhu¹, Xandra O. Breakefield¹, Johan Skog^1,2
Affiliations: ¹Department of Neurology, Neurosurgery and Radiology, Massachusetts General Hospital and Program in Neuroscience, Harvard Medical School, Boston, MA, USA; ²Exosome Diagnostics, New York, NY, USA; ³Department of Neuroscience and Pharmacology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands; ⁴Division of Neurological Surgery, UCSD School of Medicine, San Diego, CA, USA

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