A Novel Urine Exosome Gene Expression Assay to Predict High-Grade Prostate Cancer at Initial Biopsy
JAMA Oncology|July 2016
Authors: McKiernan J, Donovan MJ, O’Neill V, Bentink S, Noerholm, M, Belzer Skog J, Kattan MW, Partin A, Andriole G, Brown G, Wei JT, Thompson IM Jr, Carroll P
A Prospective Adaptive Utility Trial to Validate Performance of a Novel Urine Exosome Gene Expression Assay to Predict High-grade Prostate Cancer in Patients with Prostate-speciﬁc Antigen 2–10 ng/ml at Initial Biopsy.
European Urology | September 2018
Authors: McKiernan J, Donovan MJ, Margolis E, Partin A, Carter B, Brown G, Torkler P, Noerholm M, Skog J, Shore N, Andriole G, Thompson I, Carroll P.
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers.
Nature Cell Biology | December 2018
Authors: Skog J, Wurdinger T, van Rijn S, Meijer D, Gainche L, Sena-Esteves M, Curry Jr. WT, Carter RS, Krichevsky AM, Breakefield XO
Liquid Biopsies Using Plasma Exosomal Nucleic Acids and Plasma Cell-Free DNA Compared with Clinical Outcomes of Patients with Advanced Cancers
Clinical Cancer Research | October 2017
Authors: Mӧhrmann L, Huang HJ, Hong DS, Tsimberidou AM, Fu S, Piha-Paul SA, Subbiah V, Karp DD, Naing A, Krug A, Enderle D, Priewasser T, Noerholm M, Eitan E, Coticchia C, Stoll G, Jordan LM, Eng C, Kopetz ES, Skog J, Meric-Bernstam F, Janku F
A molecular signature for PCA3 and ERG exosomal RNA from non-DRE urine is predictive of initial prostate biopsy result.
Prostate Cancer and Prostatic Diseases | September 2015
Authors: Donovan MJ, Noerholm M, Bentink S, Belzer S, Skog J, O’Neill V, Cochran, JS, Brown GA
Liquid biopsy for cancer screening, patient stratification and monitoring.
Translational Cancer Research | June 2015
Authors: Brock G, Castellanos-Rizaldos E, Hu L, Coticchia C, Skog J
Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease.
Kidney International | July 2010
Authors: Miranda KC, Bond DT, McKee M, Skog J, Păunescu TG, Da Silva N, Brown D, Russo LM
Performance of a validated urine exosome gene expression test (EPI) in men within the USPSTF suggested age-group of 55 to 69 years at initial biopsy with a PSA 2-10 ng/mL
ASCO | February 2019
Authors: Donovan MJ, Noerholm M, Torkler P, Skog, Margolis E, Brown GA, McKiernan JM
Extended validation results from a prospective adaptive utility trial confirm performance of a novel urine exosome gene expression assay to predict high-grade prostate cancer at initial biopsy.
European Urology | April 2018
Authors: McKiernan J, Donovan MJ, Margolis E, Partin A, Carter B, Brown G, Torkler P, Noerholm M, Bentis C, Skog J, Shore N, Thompson I, Andriole G, Carroll P
Performance of a clinically validated urine exosome gene expression test to predict high grade prostate cancer in men with a prior negative biopsy.
Journal Clinical Oncology | 2018
Authors: Donovan MJ, Torkler P, Noerholm M, Skog J, McKiernan JM
Development of a clinical implementation plan (CarePath) for a novel urine exosome gene expression assay as part of a two-cohort, adaptive decision impact utility trial
AUA | May 2018
Authors: McKiernan J, Donovan MJ, Partin A, Carter B, Brown A, Torkler P, Noerholm M, Bentis C, Skog J, Shore N, Andriole G, Etzioni R, Thompson I, Carroll P
Exosomal liquid biopsy reveals mRNA and lincRNA biomarkers in early stage breast cancer patient plasma
AACR | April 2018
Authors: Chakrabortty SK, Kitchen RR, Coticchia CM, Eitan E, Valentino MD, Tadigotla VR, Castellanos-Rizaldos E, Bedford L, Uchiyama H, Badola S, Colafemina N, Morken M, Williams M, Vincent S, Yu S, Danaee H, Skog J
Radical prostatectomy outcomes from a validated urine exosome gene expression assay which predicts high-grade (GS7) prostate cancer suggests utility for men enrolled in Active Surveillance
AUA | May 2017
Authors: Donovan MJ, Torkler P, Bentis C, Noerholm M, Skog J, McKiernan J
Performance of a validated urine exosome gene expression assay to predict high-grade prostate cancer utilizing the ‘International Society of Urological Pathology’ (ISUP) 2014 grading system
ASCO GU | Feb 2017
Authors: Donovan M, Torkler P, Skog, Tisel B, Noerholm M, Carroll P